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Blake has worked as both an entrepreneur and a venture investor. He currently serves as Vice President and Senior Associate at Harris & Harris Group, Inc., an early-stage venture capital firm. Blake specializes in working with early stage companies, including acting as COO of TARA Biosystems, Inc. He also sits on the Board of Promuc, Inc.; Interome, Inc.; and Synglyco, Inc.

Prior to joining H&H, Blake was the 7th employee at HZO, Inc., leading their R&D, commercialization and technical business development efforts.

He holds degrees in Materials Science and Engineering from Cornell University (B.Sc.) and Northwestern University (Ph.D.) and a Certificate in Management for Scientists and Engineers from the Kellogg Business School.